Untap, Upkeep, Attack with Skeletal Kathari. If no responses (aside from you gaining 1 with chalice), done.
With 1 card left in your hand, do you have a way to stop this or are you going to make me play this out?
Spidey: 24/16 then 17
Hand: 1
Battlefield:
(TU) Plains x2
(TUU) Island x3
(TUU) Swamp x2
(T) Forest
(UU) Mt x2
(U) Jungle Shrine
(U) Marble Chalice (T: I gain 1 life)
Graveyard: Resounding Thunder, Steward of Valeron, Agony Warp, Resounding Roar, Cancel, Naturalize, Spell Snip, Grixis Battlemage, Puppet Conjurer, Thorn-Thrash Viashino
Exile: Kathari Screecher
Ransac: 9
Hand: 2
Battlefield:
(UUUU) Plains
(U) Forest
(UU) Island
(UU) Swamp
(U) Mountain
(U) Esper Panorama (T: 1. 1,T, Sacrifice Esper Panorama: Search your library for a basic Plains, Island, or Swamp card and put it onto the battlefield tapped. Then shuffle your library.)
(U) Obelisk of Jund (T: B/R/G)
(T) Skeletal Kathari (8/7, Flying, B, Sacrifice a creature: Regenerate Skeletal Kathari.) 5 +1/+1 counters
(U) Welkin Guide (2/2, flying, When Welkin Guide enters the battlefield, target creature gets +2/+2 and gains flying until end of turn.)
Graveyard: Qasali Ambusher, Knight of the Skyward Eye, Resounding Scream, Fire-field Ogre, Coma Veil, Soul's Fire, Realm Razer, Soul's Might, Esper Battlemage
Exile:
Ransac, cpa trash man